Restoring tolerance to gliadin may cure people of Coeliac disease

Welcome to Your Gluten Free Life. It seems that every month brings another promise of a cure for Coeliac Disease. This month some researchers at the University of Helsinki are reporting on some research that targets the gliadin component of gluten.

Gliadin is a part of the gluten protein that causes Coeliac Disease. For some reason, people who are predisposed to Coeliac Disease become intolerant to gluten and gliadin. A failure in the regulation of certain lymphocytes within the immune system causes this intolerance, and the only known “cure” is never to eat wheat, oats, barley or rye again.

Kind of along the lines of attempts to reprogram people who are allergic to peanuts by feeding them minuscule amounts of peanut protein and gradually increasing the dose, researchers have found that developing nanoparticles of gliadin and injecting them into mice significantly reduced gliadin-specific T cell activation, inflammation and tissue damage.

The results were so promising that the researchers claim that is may be possible to “reprogram” the immune systems of people with Coeliac Disease and allow them to tolerate gluten again.

Early clinical trials are now underway in the US, and the results certainly look promising. So my dream of one day eating cronuts may still come true!

We’re Going Vegan This Month

Gluten-free Teriyaki Tofu
Gluten-free Teriyaki Tofu

It’s not a deliberate thing, it just comes about because I am a vegetarian and happen to love Teriyaki Tofu. The problem is, it can be risky ordering it at a Japanese restaurant in case they coat the tofu in wheat batter. So I’ve learned to make it myself at home and thought I’d share my recipe with you. So here you go – delicious Teriyaki Tofu to make in the comfort of your own home.

And I decided I might as well go the whole hog and make vegan biscuits (or cookies if you prefer). I’ve read about aquafaba and decided I’d give it a go and make some coconut macaroons. It took some experimenting but I did manage it successfully enough that I had to fight my non-vegetarian, non-coeliac partner off long enough to take some photos of the results. So here you go, gluten-free, vegan coconut macaroons for you to enjoy.

And that’s your lot for this month. Take care and eat well.

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